SrasV1, Main, Exploration, bibRecord, 001797

Accessory proteins of SARS-CoV and other coronaviruses

Identifieur interne : 001797 ( Main/Exploration ); précédent : 001796; suivant : 001798

Accessory proteins of SARS-CoV and other coronaviruses

Auteurs : DING XIANG LIU [Singapour] ; TO SING FUNG [Singapour] ; Kelvin Kian-Long Chong [Singapour] ; Aditi Shukla [Allemagne] ; Rolf Hilgenfeld [Allemagne]

Source :

Antiviral research [ 0166-3542 ] ; 2014.

RBID : Pascal:14-0232439

Descripteurs français

Pascal (Inist)
- Protéine, Virus syndrome respiratoire aigu sévère, Structure.

English descriptors

KwdEn :
- Protein, Severe acute respiratory syndrome virus, Structure.

Abstract

The huge RNA genome of SARS coronavirus comprises a number of open reading frames that code for a total of eight accessory proteins. Although none of these are essential for virus replication, some appear to have a role in virus pathogenesis. Notably, some SARS-CoV accessory proteins have been shown to modulate the interferon signaling pathways and the production of pro-inflammatory cytokines. The structural information on these proteins is also limited, with only two (p7a and p9b) having their structures determined by X-ray crystallography. This review makes an attempt to summarize the published knowledge on SARS-CoV accessory proteins, with an emphasis on their involvement in virus-host interaction. The accessory proteins of other coronaviruses are also briefly discussed. This paper forms part of a series of invited articles in Antiviral Research on "From SARS to MERS: 10 years of research on highly pathogenic human coronaviruses" (see Introduction by Hilgenfeld and Peiris (2013)).

Affiliations:

Allemagne, Singapour

Links toward previous steps (curation, corpus...)

to stream PascalFrancis, to step Corpus: 000001
to stream PascalFrancis, to step Curation: 000986
to stream PascalFrancis, to step Checkpoint: 000016
to stream Main, to step Merge: 001803
to stream Main, to step Curation: 001797

Le document en format XML

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<author><name sortKey="Ding Xiang Liu" sort="Ding Xiang Liu" uniqKey="Ding Xiang Liu" last="Ding Xiang Liu">DING XIANG LIU</name>
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<author><name sortKey="To Sing Fung" sort="To Sing Fung" uniqKey="To Sing Fung" last="To Sing Fung">TO SING FUNG</name>
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<author><name sortKey="Chong, Kelvin Kian Long" sort="Chong, Kelvin Kian Long" uniqKey="Chong K" first="Kelvin Kian-Long" last="Chong">Kelvin Kian-Long Chong</name>
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<sZ>1 aut.</sZ>
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<author><name sortKey="Chong, Kelvin Kian Long" sort="Chong, Kelvin Kian Long" uniqKey="Chong K" first="Kelvin Kian-Long" last="Chong">Kelvin Kian-Long Chong</name>
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<wicri:noRegion>23538 Lübeck</wicri:noRegion>
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<series><title level="j" type="main">Antiviral research</title>
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<front><div type="abstract" xml:lang="en">The huge RNA genome of SARS coronavirus comprises a number of open reading frames that code for a total of eight accessory proteins. Although none of these are essential for virus replication, some appear to have a role in virus pathogenesis. Notably, some SARS-CoV accessory proteins have been shown to modulate the interferon signaling pathways and the production of pro-inflammatory cytokines. The structural information on these proteins is also limited, with only two (p7a and p9b) having their structures determined by X-ray crystallography. This review makes an attempt to summarize the published knowledge on SARS-CoV accessory proteins, with an emphasis on their involvement in virus-host interaction. The accessory proteins of other coronaviruses are also briefly discussed. This paper forms part of a series of invited articles in Antiviral Research on "From SARS to MERS: 10 years of research on highly pathogenic human coronaviruses" (see Introduction by Hilgenfeld and Peiris (2013)).</div>
</front>
</TEI>
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<li>Singapour</li>
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Accessory proteins of SARS-CoV and other coronaviruses

Accessory proteins of SARS-CoV and other coronaviruses

Source :

Descripteurs français

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri